The Mediator Release Test (MRT) is considered the number 1 blood analysis food sensitivity test. With over 4.5 million tests performed since its creation, it is the most accurate and reliable food sensitivity test. It provides a functional measurement of diet-induced sensitivity pathways. It measures how white blood cells (this is what the body releases when it thinks there is a threat) in your body react to each food.
MRT simplifies a highly complex reaction and translates that into the most useable clinical information you can get – quantifying the inflammatory response to foods and food-chemicals. Not only does MRT give insight into inflammation provoking foods and food-chemicals, but more importantly MRT identifies your BEST foods.
MRT is a indirect method of accurately measuring mediator release. MRT does this by measuring changes in the liquids to solids ratio of your blood after your blood has been exposed and incubated with the test substance. It accounts for all reactions by your immunce cells. This is done as an indicator that your immune cells have released chemical mediators such as histamines and others. Significant reactions are broken into either reactive (red) or moderately reactive (yellow) categories while any insignificant reactions (green) are placed in the low reactive category. All measurements are made using the most accurate method of measurement (Ribbon technology) currently available.
In short yes. A blinded peer reviewed scientific study conducted by the Polish Pediatric Association showed MRT to have the highest level of accurancy of any food intolerance blood test (94.5% sensitivty and 91.8% specificity).
There are a few different tests available to identify food sensitivities. The most common are IgG tests and the ALCAT.
IgG testing: These tests quantify how much IgG you are producing for a specific food, with the assumption that high levels of IgG are only a bad thing. There is a specific type of immune reaction called Type 3 Hypersensitivity that can involve IgG or another antibody called IgM. When IgG is involved in triggering mediator release, this testing will be very helpful. Unfortunately, there are three very serious limitations of IgG testing (and why we belive this is not the right test for food sensitivities).
1 - High levels of IgG can be either good (suppressing of an immune response) or bad (causing an immune response). But there is no way to differentiate between good IgG and bad IgG through any of the tests. So you may have a high level of IgG present but this might actually be a good thing.
2 - IgG only plays a minor role in IBS, migraine and fibromyalgia. Instead, research shows that Type 4 Hypersensitvity is the primary type of reaction and Type 4 Hypersensitvity does not involve IgG or any other antibody.
3 - IgG testing cannot identify reactions to checmicals like food additives. It's clearly documented that food chemicals play a very important role in provoking symptoms for many conditions. If you cannot indentify these reactions, you could very well be missing vital information that could impact your health.
How MRT compares to IgG: There are a number of advantages of the MRT over any form of IgG testing. MRT is an endpoint test, meaning that all the adverse reactions end up causing mediator release. So the MRT does this without caring about the mechanism. In fact the MRT is able to take into account the actions of all mechanisms, whether they are anitbodies or other, because all of them ultimately will cause white blood cells to release mediators. MRT is able to account for a much wider array of reactions than the reltively simple IgG testing. In addition, MRT is able to identify reactions to chemicals. Overall the MRT is unequivocally more accurate and useful clinically than IgG testing.
ALCAT Test: This test was created by the same person who invented and patented the MRT test (Dr. Mark Pasula). Dr Pasula actually invented the ALCAT before the MRT but as technology improved he was able to create the MRT test and that is why studies have shown the MRT to be more accurate (higher sensitivity and specificity) and to have a higher split sample reproducibility.
A food sensitivity is when the body has a milder reaction (when compared to an allergy) to a certain food or ingredient/additive. These are a lot more common than expected and it is only because the person fails to identify the reaction that they think they do not suffer from any. This is because the symptoms are milder and not immediate and can be delayed for a few days making it hard to identify the source. However, if left untreated and exposure continues over a long period of time the consequences can be severe.
No. When you have a food allergy, your immune system causes the reaction and it is usually immediate and severe. If you have a food sensitivity, the reaction is triggered by the digestive system, is milder and there can be a delay in the symptoms showing.
The blood draw is a meticulous procedure and we understand that problems can arise during the session. If this happens we are happy to issue you another test kit, free of charge, so you can attempt the blood draw again. Please contact our bookings team on email@example.com to arrange another test kit delivery.
Most patients see a noticeable difference within the first 1-2 weeks on the profram, however, in some cases it can take as long as 4-6 weeks. Your particular response may vary depending on certain factors:
How closely you follow your plan - If you follow it by the letter (ie. avoid all the foods you shouldn't be eating) then you will have the greatest chance of success in the shortest time frame possible. If you follow it loosely or carelessly then your results will be compromised to the extent of your neglect.
How long standing your condition has been - Sometimes it takes more time to reverse the damage caused by years of sensitivity reactions, improper eating and inadequate nutrition. The vast majority of our patients experience great results within 2 weeks to 1 month of following the plan closely.
The degree to which food sensitivity plays a role in your condition - Some of our patients come to us and experience total symptom relief from their condition as long as they maintain the correct diet. Others will experience a decrease in symptoms but not complete remission. This is because food sensitivity can either be the direct cause OR a contributing factor to your health problem.
All of these factors will affect your progress and response. However, out of all of these factors, your compliance has the highest bearing on the benefits you'll experience.
MRT identifies foods and food substances involved in food intolerances(which are different to allergies). If you know that you are allergic to a particular food, it most likely won't show up on the MRT because mast cells, the main cells involved in allergic reactions are found in tissue and not in the circulation. This is why the MRT measures the circulation cells as these are the type of cells that tend to be involved in intolerances.
It is important to always avoid foods that cause your immune system to react. The best way to be sure that a reactive food is safe again is to "challenge" it after a period of abstinence, usually 3-6 months. In some cases it may be important to retest to see if reactions have changed, as is often the case with intolerance reactions and this is why we advise carrying out the test every 6-12 months.
Eating the foods from your red or yellow list can potentially set you back weeks. The foods listed as red are those that show the highest levels of reactions from your test results and are the ones that are most likely to cause or contribute to your health problems. Eating the foods on your red list is a sure fire way to sabotage your results. After eating foods from their red list many patients often report some type of symptoms that accompanied their mistake. Headaches, brain fatigue, diarrhea, heartburn, feeling lousy, water retention and suddent weight gain are all common symptoms that arise when a person reintroduces reactive foods.
We are happy to cancel all orders and issue a full refund BEFORE the blood sample has been taken and all contents of the package are undamaged. If the blood vials have been used then we are unable to issue any refund. Should you wish to cancel your order please contact our bookings team on firstname.lastname@example.org